Youhua Liu Selected Research

Ureteral Obstruction

1/2020	Tubule-derived exosomes play a central role in fibroblast activation and kidney fibrosis.
10/2018	Targeted inhibition of the type 2 cannabinoid receptor is a novel approach to reduce renal fibrosis.
1/2018	IL-17 Receptor Signaling Negatively Regulates the Development of Tubulointerstitial Fibrosis in the Kidney.
12/2015	Klotho Ameliorates Kidney Injury and Fibrosis and Normalizes Blood Pressure by Targeting the Renin-Angiotensin System.
8/2015	GQ5 Hinders Renal Fibrosis in Obstructive Nephropathy by Selectively Inhibiting TGF-β-Induced Smad3 Phosphorylation.
12/2014	Klotho suppresses renal tubulo-interstitial fibrosis by controlling basic fibroblast growth factor-2 signalling.
4/2013	Loss of Klotho contributes to kidney injury by derepression of Wnt/β-catenin signaling.
5/2012	Tubular cell dedifferentiation and peritubular inflammation are coupled by the transcription regulator Id1 in renal fibrogenesis.
2/2012	MiR-382 targeting of kallikrein 5 contributes to renal inner medullary interstitial fibrosis.
9/2011	Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Youhua Liu Research Topics

Disease

63	Fibrosis (Cirrhosis) 02/2022 - 01/2002
26	Proteinuria 02/2022 - 08/2006
24	Chronic Renal Insufficiency 01/2022 - 10/2002
18	Inflammation (Inflammations) 01/2021 - 03/2007
17	Acute Kidney Injury (Acute Renal Failure) 02/2022 - 02/2002
17	Ureteral Obstruction 01/2020 - 01/2002
16	Kidney Diseases (Kidney Disease) 01/2022 - 05/2008
13	Albuminuria 01/2022 - 08/2006
13	Reperfusion Injury 01/2021 - 09/2013
10	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 06/2004
8	Wilms Tumor (Wilm's Tumor) 01/2022 - 06/2010
7	Obesity 11/2022 - 01/2019
7	Ischemia 12/2021 - 09/2012
5	Neoplasms (Cancer) 08/2020 - 04/2002
4	Hypertension (High Blood Pressure) 10/2020 - 03/2016
3	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2013 - 09/2009
2	Hypertrophy 01/2022 - 12/2018
2	Disease Progression 01/2021 - 10/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 10/2019
2	Neoplasm Metastasis (Metastasis) 08/2020 - 04/2014
2	Wounds and Injuries (Trauma) 05/2020 - 10/2015
2	IGA Glomerulonephritis (IGA Nephropathy) 01/2020 - 09/2014
2	Insulin Resistance 01/2019 - 01/2006
2	Cardiovascular Diseases (Cardiovascular Disease) 08/2010 - 10/2009
2	Cicatrix (Scar) 12/2009 - 01/2006
2	Hepatocellular Carcinoma (Hepatoma) 10/2006 - 04/2002
2	Hyperglycemia 08/2005 - 07/2003
2	Carcinogenesis 10/2004 - 05/2004
1	Body Weight (Weight, Body) 11/2022

Drug/Important Bio-Agent (IBA)

37	CateninsIBA 02/2022 - 01/2011
17	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 09/2009
15	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2002
15	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 10/2021 - 01/2002
9	ICG 001IBA 01/2022 - 09/2011
9	CollagenIBA 01/2019 - 11/2002
9	Fibronectins (Fibronectin)IBA 01/2019 - 11/2002
8	nephrinIBA 01/2022 - 02/2008
8	CreatinineIBA 01/2019 - 01/2013
7	CytokinesIBA 01/2022 - 01/2002
7	Advanced Oxidation Protein Products (AOPP)IBA 01/2022 - 12/2009
7	Matrix Metalloproteinase 7 (Matrilysin)IBA 01/2020 - 02/2012
6	Vitamin D FDA LinkGeneric 01/2011 - 12/2006
6	Transforming Growth Factor beta1 (TGF beta 1)IBA 08/2010 - 01/2002
5	Angiotensin IIIBA 01/2019 - 10/2002
5	Messenger RNA (mRNA)IBA 01/2013 - 05/2003
4	Streptozocin (Streptozotocin)FDA Link 01/2022 - 07/2003
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022 - 07/2004
4	6-methyladenineIBA 01/2022 - 01/2019
4	Cisplatin (Platino)FDA LinkGeneric 12/2021 - 09/2013
4	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021 - 02/2002
4	PPAR gammaIBA 01/2020 - 10/2004
4	Small Interfering RNA (siRNA)IBA 01/2020 - 10/2012
4	Insulin (Novolin)FDA Link 01/2019 - 07/2003
4	LigandsIBA 01/2019 - 01/2006
4	paricalcitol (Zemplar)FDA Link 01/2011 - 12/2006
4	Transforming Growth Factor beta (TGF-beta)IBA 05/2008 - 05/2003
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2017
3	NPHS2 proteinIBA 01/2022 - 01/2011
3	TenascinIBA 01/2020 - 03/2017
3	Glycoproteins (Glycoprotein)IBA 01/2020 - 08/2010
3	salicylhydroxamic acid (SHAM)IBA 01/2020 - 05/2003
3	Plasminogen Activators (Plasminogen Activator)IBA 01/2019 - 08/2010
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 08/2005
3	AlbuminsIBA 01/2018 - 01/2013
3	DesminIBA 01/2017 - 02/2008
3	Proto-Oncogene Proteins c-metIBA 09/2013 - 01/2005
3	integrin-linked kinaseIBA 08/2010 - 08/2006
3	beta CateninIBA 09/2009 - 10/2006
3	Tissue Plasminogen Activator (Alteplase)FDA Link 05/2008 - 11/2002
2	Peptides (Polypeptides)IBA 01/2022 - 01/2022
2	podocalyxinIBA 01/2022 - 01/2017
2	ArrestinIBA 01/2022 - 01/2021
2	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2021 - 01/2021
2	AntagomirsIBA 01/2021 - 11/2020
2	Therapeutic UsesIBA 01/2020 - 02/2003
2	plerixafor FDA Link 01/2020 - 01/2017
2	IntegrinsIBA 01/2020 - 08/2010
2	Chemokine ReceptorsIBA 01/2020 - 01/2017
2	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2019
2	AntioxidantsIBA 10/2019 - 11/2016
2	SaltsIBA 01/2019 - 11/2018
2	EnzymesIBA 08/2015 - 01/2006
2	cyclopamineIBA 10/2014 - 05/2012
2	ChemokinesIBA 09/2013 - 07/2008
2	Calcitriol Receptors (Calcitriol Receptor)IBA 10/2012 - 09/2008
2	Peptide Hydrolases (Proteases)FDA Link 06/2012 - 02/2012
2	Chemokine CCL5IBA 05/2012 - 09/2008
2	Plasminogen Activator Inhibitor 1IBA 12/2011 - 09/2011
2	Transcription Factors (Transcription Factor)IBA 02/2011 - 01/2006
2	NF-kappa B (NF-kB)IBA 09/2008 - 07/2008
1	Metformin (Glucophage)FDA LinkGeneric 11/2022
1	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 02/2022
1	Decellularized Extracellular MatrixIBA 01/2022
1	CXC ChemokinesIBA 01/2022

Therapy/Procedure

12	Therapeutics 01/2022 - 04/2002
6	Nephrectomy 01/2021 - 12/2015
3	Injections 01/2020 - 01/2002
2	Intravenous Injections 01/2022 - 02/2003
2	Denervation 01/2019 - 09/2017
2	Ligation 08/2015 - 05/2006